Serum levels of fluconazole in patients after cytotoxic chemotherapy for hematological malignancy

Alterations in serum levels of trace element in patients with breast cancer before and after chemotherapy

Background: Breast cancer is the most common serious disease around the world. The trace elements have a vital role in the metabolism and chemotherapy may change the level of metal ions. Due to the ambiguity of the existence in this regard, the study examined the trace element serum levels in women with breast cancer before and after chemotherapy . Methods: Sixty patients were studied undergoi...

Dwindled serum IgG levels of Rubella, Diphtheria toxin, Hepatitis B virus and Tetanus Toxoid after chemotherapy; a report from Iranian children with malignancy

Backgrounds: Epigenetic regulation such as DNA methylation plays a major role in chromatin organization Background: Chemotherapy suppresses immunoglobulin production as a result of cell toxicity. Decreased immunoglobulin levels can result in the onset of opportunistic infections. The aim of the current study is to compare the immunoglobulin G (IgG) levels of the selected vaccine-preventable dis...

Serum deoxythymidine kinase as a progressive marker of hematological malignancy.

The levels of serum deoxythymidine kinase (s-dTK) were investigated for 127 patients suffering hematological malignancy by a sensitive method using [125I]-iododeoxy-uridine as substrate. It was found that the deoxythymidine kinase activity in the sera of these patients was higher than the normal levels in adults. It was also found that the levels of s-dTK in the progressive stage were much high...

Title Hepatitis B reactivation after withdrawal of pre-emptive lamivudine in patients with haematological malignancy on completion of cytotoxic chemotherapy

Hepatitis B reactivation after withdrawal of pre-emptive lamivudine in patients with haematological malignancy on completion of cytotoxic chemotherapy.

BACKGROUND The hepatic outcome of hepatitis B surface antigen (HBsAg) positive patients undergoing chemotherapy after withdrawal of pre-emptive lamivudine is unknown. AIMS To examine the occurrence of hepatitis B virus (HBV) reactivation after withdrawal of pre-emptive lamivudine. METHODS Pre-emptive lamivudine was started one week before initiation of chemotherapy in 46 consecutive HBsAg p...